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Isotretinoin is commonly known under the brand name Accutane, which is the generic name that many people recognize in the context of acne treatment. Isotretinoin is a retinoid, derived from vitamin A, and is used primarily to treat severe acne that has not responded to other treatments. Knowing this is crucial because isotretinoin has specific indications and potential side effects that practitioners need to be aware of when discussing treatment options with their patients.

The other names mentioned refer to different compounds with distinct functions and uses in dermatology. Adapalene is another retinoid but is mainly used for treating acne in a more topical application form. Clindamycin is an antibiotic that may also be used for acne treatment but has a different mechanism of action. Tretinoin, although related, is mainly used for less severe acne and has different applications for skin issues like photoaging. Understanding these distinctions helps in recognizing the distinct roles that each of these medications plays in dermatological care.